| KDS 4103 |
| (3’-(aminocarbonyl)[1,1’-biphenyl]-3-yl)-cyclohexylcarbamate |
| (CAS 546141-08-6) |
 |
| Description： |
The enzyme fatty acid amide hydrolase (FAAH) is widely expressed in brain and other tissues, and is capable of hydrolyzing anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains. The enzyme fatty acid amide hydrolase (FAAH) is widely expressed in brain and other tissues, and is capable of hydrolyzing anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains. URB597 was recently synthesized and reported to be a potent and selective inhibitor of FAAH. URB597 inhibits FAAH with an IC50 of 4.6 nM in brain membranes and 0.5 nM in intact neurons. It has been demonstrated in FAAH(-/-) mice that marked depression of FAAH activity results in reduced sensation of pain and enhanced endocannabinoid signalling. URB597 exhibits both anti-nociceptive and anxiolytic effects in vivo without evoking other symptoms associated with cannabinoid-like compounds. Thus, URB597 may serve as a lead compound for the development of new analgesic and anxiolytic drugs.
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| Product No. |
KT00477 |
| Product Name |
KDS 4103 |
| Synonyms |
|
| Formal Name |
(3’-(aminocarbonyl)[1,1’-biphenyl]-3-yl)-cyclohexylcarbamate |
| CAS Number |
546141-08-6 |
| Molecular Formula |
C20H22N2O3 |
| Formula Weight |
338.4 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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