| 25,26-Dihydroxyvitamin D3 |
| 25,26-Dihydroxyvitamin D |
| (CAS 29261-12-9) |
 |
| Description： |
25,26-Dihydroxyvitamin D3(25,26-dihydroxycholecalciferol) is a metabolite of vitamin D3 with intestinal calcium transport activity.
IC50 value:
Target: VD metabolite
The biological activity of synthetic 24,25 and 25,26 diOHD3 was studied in vitamin D-deficient rats. The purpose of this study was to investigate the influence of small doses of both metabolites (0.125-0.250 mug) upon intestinal calcium transport and bone calcium mobilization. Both metabolites were able to increase calcium absorption in rats maintained on a calcium-deficient diet, but failed to do it in rats on a normal calcium diet. Bilateral nephrectomy suppressed this effect. The "bone calcium mobilization" of both derivatives was measured in vitamin D and calcium- or phosphorus-deprived rats after one intravenous dose. When serum calcium was initially low, 24,25 and 25,26 diOHD3 increased serum calcium moderately, but the increment was only significant with 24,25 diOHD3.
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| Product No. |
KT20334 |
| Product Name |
25,26-Dihydroxyvitamin D3 |
| Synonyms |
25,26-Dihydroxycholecalciferol |
| Formal Name |
25,26-Dihydroxyvitamin D |
| CAS Number |
29261-12-9 |
| Molecular Formula |
C27H44O3 |
| Formula Weight |
416.64 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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