Bleomycin sulfate |
bleomycin sulfate (salt) |
(CAS 9041-93-4) |
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Description: |
Bleomycin is a glycopeptide antitumor antibiotic produced by the bacterium S. verticillus. Its mechanism of action causes single and double-strand DNA breaks in tumor cells, which interrupts the cell cycle.Bleomycin is thought to achieve this by chelating metal ions, producing a pseudoenzyme that reacts with oxygen to produce superoxide and hydroxide free radicals that cleave DNA. Bleomycin has been used for the treatment of Hodgkin’s lymphoma in combination with doxorubicin, squamous cell carcinomas, testicular cancer, as well as in animal models of pulmonary fibrosis.
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Product No. |
KT20051 |
Product Name |
Bleomycin sulfate |
Synonyms |
Blenoxane; Bleo; Blexane |
Formal Name |
bleomycin sulfate (salt) |
CAS Number |
9041-93-4 |
Molecular Formula |
C55H84N17O21S3 • XH2SO4 |
Formula Weight |
1513.6 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
2 years |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
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