| TCS 1102 |
| (2S)-N-[1,1’-Biphenyl]-2-yl-1-[2-[(1-methyl-1H-benzimidazol-2-yl)thio]acetyl]-2-pyrrolidinecarboxamide |
| (CAS 916141-36-1) |
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| Description： |
TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for OX2 and OX1 receptors respectively).
IC50 value: 0.2 nM (Ki, OX2 receptor); 3 nM (Ki, OX1 receptor)
Target: OX2 and OX1 receptor
TCS-1102 (10 and 20 mg/kg, i.p.) were found to decrease fear and anxiety in rats 14 days after exposure to footshock.Furthermore, TCS-1102 (10 mg/kg, i.p.) was found to have anxiolytic effects that were specific for HR when tested in the elevated T-maze.
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| Product No. |
KT20321 |
| Product Name |
TCS 1102 |
| Synonyms |
TCS1102; TCS-1102 |
| Formal Name |
(2S)-N-[1,1’-Biphenyl]-2-yl-1-[2-[(1-methyl-1H-benzimidazol-2-yl)thio]acetyl]-2-pyrrolidinecarboxamide |
| CAS Number |
916141-36-1 |
| Molecular Formula |
C27H26N4O2S |
| Formula Weight |
470.59 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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TCS 1102
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