| JNJ1661010 |
| N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide |
| (CAS 681136-29-8) |
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| Description： |
Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines, including the endocannabinoid arachidonoyl ethanolamide (AEA). JNJ-1661010 is a selective inhibitor of FAAH (IC50s = 34 and 33 nM in rat and human, respectively) that is able to cross the blood-brain barrier. At 20 mg/kg, JNJ-1661010 has been shown to elevate levels of AEA in rat brain. This compound has been used to examine the contribution of endocannabinoid signaling in experimental fibrosis.
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| Product No. |
KT00467 |
| Product Name |
JNJ1661010 |
| Synonyms |
|
| Formal Name |
N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide |
| CAS Number |
681136-29-8 |
| Molecular Formula |
C19H19N5OS |
| Formula Weight |
365.5 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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