| Seratrodast |
| 7-(3,5,6-Trimethy1-1,4-benzoquinon-2-y1)-7-phenylheptanoic acid; 7-Phenyl-7-(2,4,5-trimethyl-3,6-dioxo-1-cyclohexa-1,4-dienyl)heptanoic acid; 5-(2,4,5-Trimethyl-3,6,-dioxo-1,4-cyclohexadien-1-yl)benze |
| (CAS 112665-43-7) |
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| Description： |
Seratrodast is a potent and selective thromboxane A2 receptor (TP) antagonist.
Seratrodast is a potent antagonist of the thromboxane A2 (TXA2) receptor (TP), blocking specific binding of U-46619 to guinea pig platelets with an IC50 value of 7.4 nM and platelet aggregation induced by U-44069 with an IC50 value of 350 nM.It is metabolized, in liver microsomes, by cytochrome P450 (CYP) isoforms 3A and 2C9/10, with a minor contribution from CYP2C8 and CYP2C19.Seratrodast is commonly used to study the roles of the TP receptor in animal airways and in tissue samples.
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| Product No. |
KT00826 |
| Product Name |
Seratrodast |
| Synonyms |
A-73001；ABT-001；AA2414 |
| Formal Name |
7-(3,5,6-Trimethy1-1,4-benzoquinon-2-y1)-7-phenylheptanoic acid; 7-Phenyl-7-(2,4,5-trimethyl-3,6-dioxo-1-cyclohexa-1,4-dienyl)heptanoic acid; 5-(2,4,5-Trimethyl-3,6,-dioxo-1,4-cyclohexadien-1-yl)benze |
| CAS Number |
112665-43-7 |
| Molecular Formula |
C22H26O4 |
| Formula Weight |
354.44 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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