HMR-1275 |
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(CAS 146426-40-6) |
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Description: |
Alvocidib (INN; also known as Flavopiridol or HMR-1275) is a flavonoid alkaloid CDK9 kinase inhibitor under clinical development for the treatment of chronic lymphocytic leukemia, by Sanofi. It has been studied also for the treatment of arthritis and atherosclerotic plaque formation The target of Flavopiridol is the positive transcription elongation factor P-TEFb. Treatment of cells with Flavopiridol leads to inhibition of P-TEFb and the loss of mRNA production.
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Product No. |
KT00430 |
Product Name |
HMR-1275 |
Synonyms |
L-868275,HL 275,Alvocidib |
Formal Name |
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CAS Number |
146426-40-6 |
Molecular Formula |
C21H20ClNO5 |
Formula Weight |
401.84 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
2 years |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
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