| RU 24969 |
| 5-Methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole;1Hindole, 5methoxy3(1,2,3,6tetrahydro4pyridinyl); 5methoxy3(1,2,3,6tetrahydropyridin4yl)1Hindole; 5Methoxy3(1,2,3,6tetrahydropyridin4yl)1Hindole |
| (CAS 66611-26-5) |
 |
| Description： |
RU 24969 is a selective agonist at the 5-HT1A and 5-HT1B receptors.
IC50 value:
Target: 5-HT1A/1B agonist
RU 24969 possesses preference for the purported 5-HT1B subtype of central 5-HT1 recognition site. The reported significant linear correlation between hypotensive activity following intravenous (i.v.) administration to anesthetized rats and affinity for the central 5-HT1 binding site could only be maintained by incorporation of the affinity of RU 24969 for its low and 8-OH-DPAT for its high affinity binding site .The drug RU 24969 (10 mg/kg) inhibited the rate of synthesis of 5-HT in rat brain by about 50%. Pretreatment of rats with desmethylimipramine over a longer term or clenbuterol given acutely, treatments known to enhance the behavioural responses of rats to various other 5-HT agonists, did not alter the RU 24969-induced response. RU 24969 (0.03-3.0mg/kg, s.c.) dose-dependently decreased water consumption in water deprived rats.
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| Product No. |
KT20288 |
| Product Name |
RU 24969 |
| Synonyms |
RU24969; RU-24969 |
| Formal Name |
5-Methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole;1Hindole, 5methoxy3(1,2,3,6tetrahydro4pyridinyl); 5methoxy3(1,2,3,6tetrahydropyridin4yl)1Hindole; 5Methoxy3(1,2,3,6tetrahydropyridin4yl)1Hindole |
| CAS Number |
66611-26-5 |
| Molecular Formula |
C14H16N2O |
| Formula Weight |
228.29 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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