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GW 6471 
N-​[(2S)-​2-​[[(1Z)-​1-​methyl-​3-​oxo-​3-​[4-​(trifluoromethyl)phenyl]-​1-​propen-​1-​yl]amino]-​3-​[4-​[2-​(5-​methyl-​2-​phenyl-​4-​oxazolyl)ethoxy]phenyl]propyl]-​propanamide
(CAS 880635-03-0)
Description:

The peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor that regulates the expression of genes involved in fatty acid metabolism, lipoprotein synthesis and metabolism, and inflammation. GW 6471 is an antagonist of PPARα (IC50 = 240 nM). It drives the displacement of coactivators from PPARα and promotes the recruitment of co-repressor proteins like nuclear co-repressor. GW 6471 is used in cell-free, cell lysate, and whole cell systems to examine the impact of PPARα antagonism.

 

Product No. KT00417 
Product Name GW 6471 
Synonyms
Formal Name N-​[(2S)-​2-​[[(1Z)-​1-​methyl-​3-​oxo-​3-​[4-​(trifluoromethyl)phenyl]-​1-​propen-​1-​yl]amino]-​3-​[4-​[2-​(5-​methyl-​2-​phenyl-​4-​oxazolyl)ethoxy]phenyl]propyl]-​propanamide
CAS Number 880635-03-0
Molecular Formula C35H36F3N3O4
Formula Weight 619.7
Formulation A crystalline solid
Purity 98%min
Stability 2 years
Storage -20°C
Shipping USD45 for Europe and USA. No shipping charge once amount reach USD500
Quality Control HNMR,CNMR,LCMS,HPLC,IR,etc.
Price & Availability In Stock. Price Negotiated.
 
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