GW 6471 |
N-[(2S)-2-[[(1Z)-1-methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propen-1-yl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]propyl]-propanamide |
(CAS 880635-03-0) |
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Description: |
The peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor that regulates the expression of genes involved in fatty acid metabolism, lipoprotein synthesis and metabolism, and inflammation. GW 6471 is an antagonist of PPARα (IC50 = 240 nM). It drives the displacement of coactivators from PPARα and promotes the recruitment of co-repressor proteins like nuclear co-repressor. GW 6471 is used in cell-free, cell lysate, and whole cell systems to examine the impact of PPARα antagonism.
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Product No. |
KT00417 |
Product Name |
GW 6471 |
Synonyms |
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Formal Name |
N-[(2S)-2-[[(1Z)-1-methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propen-1-yl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]propyl]-propanamide |
CAS Number |
880635-03-0 |
Molecular Formula |
C35H36F3N3O4 |
Formula Weight |
619.7 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
2 years |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
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