| Olanzapine |
| 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine |
| (CAS 132539-06-1) |
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| Description： |
Olanzapine is an antipsychotic, thienobenzodiazepine compound that has been approved for use in the treatment of schizophrenia and bipolar disorder (formulated for human use under the name Zyprexa®). Olanzapine binds as an antagonist/inverse agonist to dopamine D1 (Ki = 31 nM), dopamine D2 (Ki = 11 nM), dopamine D4 (Ki = 27 nM), serotonin 5-HT2A (Ki = 4 nM), serotonin 5-HT2C (Ki = 11 nM), serotonin 5-HT3 (Ki = 57 nM), muscarinic M1 (Ki = 2 nM), α1-adrenergic (Ki = 19 nM), and histamine H1 (Ki = 7 nM) receptors. Olanzapine has a high affinity for dopamine D1 and D2 receptors (IC50s = 25 and 10 nM, respectively) in human striatal tissue and for 5-HT2A, 5-HT2C, muscarinic M1, and α1-adrenergic receptors (IC50s = 7, 71, 2, and 70 nM, respectively) in human frontal cortex.This product is intended for research purposes only.
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| Product No. |
KT20267 |
| Product Name |
Olanzapine |
| Synonyms |
Zyprexa; LY170053; LY-170053; LY 170053 |
| Formal Name |
2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine |
| CAS Number |
132539-06-1 |
| Molecular Formula |
C17H20N4S |
| Formula Weight |
312.4 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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