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Mirtazapine 
(RS)-1,2,3,4,10,14b-Hexahydro-2-methylpyrazino-[2,1-a]pyrido[2,3-c][2]benzazepine
(CAS 85650-52-8)
Description:

Mirtazapine is a potent tetracyclic antidepressant.
Target: 5-HT Receptor
Mirtazapine, the novel antidepressant, has a dual mode of action. It is a noradrenergic and specific serotonergic antidepressant (NaSSA) that acts by antagonizing the adrenergic alpha2-autoreceptors and alpha2-heteroreceptors as well as by blocking 5-HT2 and 5-HT3 receptors.Mirtazapine appears to have a substantial ameliorating effect on hot flushes and perspiration bouts. It is postulated that the 5-HT(2A) blocking properties of mirtazapine is accounted in the symptomatic relief of hot flushes. After 4-24 weeks of treatment, mirtazapine induced downregulation of platelet alpha(2A)-adrenoceptors (up to 34%) and Galphai proteins (up to 28%), and the upregulation of GRK 2 (up to 30%). Treatment with mirtazapine reversed this abnormality and induced downregulation of alpha(2A)-adrenoceptor/Galphai complex.

 

Product No. KT20262 
Product Name Mirtazapine 
Synonyms Remeron; SolTab; Zispin; Org3770; 6-Azamianserin; Avanza
Formal Name (RS)-1,2,3,4,10,14b-Hexahydro-2-methylpyrazino-[2,1-a]pyrido[2,3-c][2]benzazepine
CAS Number 85650-52-8
Molecular Formula C17H19N3
Formula Weight 265.35
Formulation A crystalline solid
Purity 98%min
Stability 2 years
Storage -20°C
Shipping USD45 for Europe and USA. No shipping charge once amount reach USD500
Quality Control HNMR,CNMR,LCMS,HPLC,IR,etc.
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