Fluoxetine |
(+/-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine |
(CAS 54910-89-3) |
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Description: |
Fluoxetine(LY110140) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI)class.
Target: SSRIs
Fluoxetine is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Fluoxetine delays the reuptake of serotonin, resulting in serotonin persisting longer when it is released. Fluoxetine may also produce some of its effects via its weak 5-HT2C receptor antagonist effects. Fluoxetine displayed relatively high affinity for the 5-HT2C receptor in the choroid plexus, with a Ki value for inhibition of [3H]mesulergine binding of 55.4 nM. [3H]Ketanserin (5-HT2A) binding assays revealed that the SSRIs fluoxetine, norfluoxetine and citalopram show 10- to 23-fold selectivity for the 5-HT2C receptor in vitro, whereas the TCA imipramine does not. In addition, fluoxetine has been found to act as an agonist of the σ1-receptor, with a potency greater than that of citalopram but less than that of fluvoxamine.
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Product No. |
KT20245 |
Product Name |
Fluoxetine |
Synonyms |
Prozac; LY110140; LY-110140; LY 110140 |
Formal Name |
(+/-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine |
CAS Number |
54910-89-3 |
Molecular Formula |
C17H18F3NO |
Formula Weight |
309.33 |
Formulation |
A crystalline solid |
Purity |
98%min |
Stability |
2 years |
Storage |
-20°C |
Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
Price & Availability |
In Stock. Price Negotiated. |
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