| Suvorexant |
| 5-Chloro-2-[(5R)-5-methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl]-1,3-benzoxazole |
| (CAS 1030377-33-3) |
 |
| Description： |
Suvorexant is a potent dual OX receptor antagonist with Ki of 0.55 nM and 0.35 nM for OX1 receptor and OX2 receptor, respectively.
Suvorexant has excellent passive permeability and oral bioavailability, and induces favorable sleep effects in rats.In addition, suvorexant significantly and dose-dependently reduces locomotor activity and promotes sleep in rats (10, 30, and 100 mg/kg), dogs (1 and 3 mg/kg), and rhesus monkeys (10 mg/kg).
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| Product No. |
KT00866 |
| Product Name |
Suvorexant |
| Synonyms |
MK 4305; MK-4305; MK4305 |
| Formal Name |
5-Chloro-2-[(5R)-5-methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl]-1,3-benzoxazole |
| CAS Number |
1030377-33-3 |
| Molecular Formula |
C23H23ClN6O2 |
| Formula Weight |
450.92 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500 |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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