| Vinorelbine |
| 3’,4’-Didehydro-4’-deoxy-C’-norvincaleukoblastine |
| (CAS 71486-22-1) |
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| Description： |
Vinorelbine(KW-2307 base) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.
IC50 value:
Target: Anti-mitotic
Vinorelbine (Navelbine) is the first 5′NOR semi-synthetic vinca alkaloid and exerts its activity through the MAPK (p38) pathway with median IC90 and IC50 of 15.5 and 2.3 μM. Vinorelbine induces concentration- and time-dependent increases in the protein levels of both p53 and p21 in hormone-dependent (AD) LNCaP cells, and can restore p21 expression in androgen-independent (AI) prostate cancer cells through both p53-dependent and-independent pathways.
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| Product No. |
KT20026 |
| Product Name |
Vinorelbine |
| Synonyms |
Navelbine; Navelbine base; KW-2307 base |
| Formal Name |
3’,4’-Didehydro-4’-deoxy-C’-norvincaleukoblastine |
| CAS Number |
71486-22-1 |
| Molecular Formula |
C45H54N4O8 |
| Formula Weight |
778.93 |
| Formulation |
A crystalline solid |
| Purity |
98%min |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
USD45 for Europe and USA. No shipping charge once amount reach USD500. |
| Quality Control |
HNMR,CNMR,LCMS,HPLC,IR,etc. |
| Price & Availability |
In Stock. Price Negotiated. |
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